PharmacyCodes



Carbidopum [Inn-Latin] en es it fr

Carbidopum [Inn-Latin] Brand names, Carbidopum [Inn-Latin] Analogs

Carbidopum [Inn-Latin] Brand Names Mixture

  • Atamet (carbidopa + levodopa)
  • Sinemet (carbidopa + levodopa)

Carbidopum [Inn-Latin] Chemical_Formula

C10H14N2O4

Carbidopum [Inn-Latin] RX_link

http://www.rxlist.com/cgi/generic/sinemet.htm

Carbidopum [Inn-Latin] fda sheet

Carbidopum [Inn-Latin] msds (material safety sheet)

Carbidopum [Inn-Latin] Synthesis Reference

Chemerda et al., U.S. Pat. 3,462,536 (1963)

Carbidopum [Inn-Latin] Molecular Weight

226.229 g/mol

Carbidopum [Inn-Latin] Melting Point

203-205oC

Carbidopum [Inn-Latin] H2O Solubility

3.8 mg/L

Carbidopum [Inn-Latin] State

Solid

Carbidopum [Inn-Latin] LogP

0.494

Carbidopum [Inn-Latin] Dosage Forms

Tablet (25 mg)

Carbidopum [Inn-Latin] Indication

For treatment of the symptoms of idiopathic Parkinson's disease (paralysis agitans), post-encephalitic parkinsonism

Carbidopum [Inn-Latin] Pharmacology

Carbidopa, a noncompetitive decarboxylase inhibitor, is used in combination with levodopa for the treatment of Parkinson's disease.

Carbidopum [Inn-Latin] Absorption

Rapidly decarboxylated to dopamine in extracerebral tissues so that only a small portion of a given dose is transported unchanged to the central nervous system.

Carbidopum [Inn-Latin] side effects and Toxicity

Symptoms of a carbidopa toxicity include muscle spasms or weakness, spasms of the eyelid, nausea, vomiting, diarrhea, an irregular heartbeat, confusion, agitation, hallucinations, and unconsciousness.

Carbidopum [Inn-Latin] Patient Information

Carbidopa is used with levodopa to treat Parkinson's disease. Parkinson's disease
is believed to be related to low levels of a chemical called dopamine (DOE pa meen)
in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body.
Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa
before it can reach the brain and take effect. Carbidopa is only effective if it is
taken with levodopa. It has no effect if it is used alone. Carbidopa is used with
levodopa to treat the stiffness, tremors, spasms, and poor muscle control of
Parkinson's disease. These medications are also used to treat the same muscular
conditions when they are caused by drugs such as chlorpromazine (Thorazine),
fluphenazine (Prolixin), perphenazine (Trilafon), and others.

Carbidopum [Inn-Latin] Organisms Affected

Humans and other mammals